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Serum interleukin-6 level in unmedicated adults with attention-deficit/hyperactivity disorder – preliminary report

Zuzanna Rosa1, Joanna Woźniak1, Hanna Jerczyńska2, Jakub Kaźmierski1

Affiliacja i adres do korespondencji
Psychiatr Psychol Klin 2024; 24 (1): 69–73
DOI: 10.15557/PiPK.2024.0009
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Aim: The aim of the study was to compare adults suffering from attention-deficit/hyperactivity disorder with healthy controls, in terms of their serum concentrations of inflammatory cytokine interleukin-6. Materials and methods: The diagnosis of attention-deficit/hyperactivity disorder was established during the interview with the clinician on the basis of the Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition. A total of 36 participants with attention-deficit/ hyperactivity disorder and 28 in the control group were included. The age range was 21–55 years. Individuals with a psychiatric comorbidity, allergy, chronic inflammatory disease, and receiving psychostimulant treatment were excluded. Results: Adults diagnosed with attention-deficit/hyperactivity disorder had higher serum concentrations of interleukin-6 in comparison to healthy controls. Conclusions: The aetiology of attention-deficit/hyperactivity disorder may be influenced by the concentration of inflammatory factors.

Słowa kluczowe
ADHD, inflammation, interleukin-6