Considered a taboo topic in many societies, menopause in autistic women is still under-recognised, and little research addresses its impact. Existing studies suggest that this often-difficult transition period is associated with numerous unmet health needs and a frustrating lack of knowledge and support from healthcare professionals. Menopausal vasomotor symptoms, the hallmark of menopause, can intensify and worsen sensory sensitivities in many autistic women. We present the case of a 53-year-old Caucasian autistic woman without intellectual disability or other current psychiatric comorbidities. The patient underwent gynaecologic and hormonal lab testing, and was introduced to hormone replacement therapy to ameliorate symptoms of oestradiol and progesterone deficiency. Menopausal vasomotor symptoms experienced by the patient were monitored over a period of seven months following the implementation of hormone replacement therapy and nonpharmacologic approaches. Hormone replacement therapy decreased menopausal vasomotor symptoms, but not all her initial complains. Strong sensory issues were linked to more severe menopausal vasomotor symptoms. This case highlights the need for further research and the development of the global Extension for Community Health Outcomes (ECHO) Autism® model to advance medical care offered to autistic women during menopause.

autism spectrum disorder, menopause, autistic women, hormone replacement therapy, ECHO Autism